Series documents Murillo's career as a Ph.D. candidate at Harvard University and as a professor of Spanish literature at the University of California at Berkeley. These papers include correspondence with colleagues and publisheres, department memoranda, publications and publication off-prints.

Series documents Murillo's service as a volunteer for various Southern California law enforcement agencies, including the Los Angeles Police Department, the California Highway Patrol and the Los Angeles County Sheriff's Department. Papers include correspondence, bilingual field guides created by Murillo for officers, Spanish-English dictionaries and various publications from law enforcement agencies.